Amy Lee describes the meaning of this song in the following quote:
The End Of the Dream is, just about life, and the end of the dream is death. You know it's about the journey and it's about, again, this recurring theme of not being afraid and living while you're alive because it doesn't last forever. I think that's something that comes out a lot in our music because it's something that I deeply feel.
It's funny though cause I'm always telling it to myself. It's not like you learn something and then just go 'Yeah, totally'... You have to make a constant effort to remind yourself of things that you believe in, you know. So I feel like, yeah that theme about not being afraid and life doesn't last forever... that comes out a lot. And yeah, that song is about that.