"Lithium" is a music video for the same-titled song on The Open Door.
The music video for "Lithium", directed by Paul Fedor,was filmed between October 31 and November 1, 2006. It features Amy Lee and the band members performing in a snowy cemetery, and shows Lee representing the emotions of sorrow and happiness, and drowns in a pond of black liquid at the end of the video. The underwater scenes are similar to those of the music video for "Going Under", with the exception of the jellyfish. The setting is similar to that of the music video for AFI's "Love Like Winter". During an interview with MTV News, Lee said, “ There's the me in all white and it's really wintry, and then there's the all-in-black Amy under the surface of the water of this lake in the forest. So it's the happiness and the sorrow and we're almost singing to each other, trying to figure out how both of us can work. ” The music video premiered exclusively to Canadian audiences on MuchMusic.com on November 24, 2006, and was placed on other sites such as YouTube and Myspace afterwards. It was subsequently removed from MuchMusic.com, and restored on December 4. Wind-up initially released the video on the band's official website on November 27. It was available for digital download on iTunes on December 19. Lee made a guest appearance on TRL on December 24 to premier the video on MTV.